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Monday, 09 November 2015 00:00

Diagnosis and Treatment of TB


Tuberculosis - is widespread in the world of infectious disease, the development of which is triggered by Mycobacterium tuberculosis.

The most frequent targets of this disease are the lungs, at least - other organs and systems.

According to the World Health Organization (WHO), one third of the world's population is infected with Mycobacterium tuberculosis. Does this mean that all of them get sick? No, the disease develops in only 10% of those infected.

Important: Tuberculosis is preventable and curable.

And WHO has to prove: from 2000 to 2013, 37 million lives have been saved due to timely diagnosis and adequate treatment of the disease.

Phthisiologists Belarus - the real virtuosos of the business: in 2014 the incidence of tuberculosis in the country has decreased from 37.2 to 34.5 per 100 thousand population, the mortality rate - from 5.7 to 4.7 per 100 thousand. Belarus has everything to timely diagnosis and appropriate treatment of a patient with tuberculosis, which allows to save a person's life.

Diagnosis of tuberculosis.

1.Laboratornaya diagnosis. Belarus has been successfully operating the Republican reference laboratory, equipped with modern equipment, which employs highly trained specialists, which allows for fast and reliable bacteriological diagnosis, which includes:

• smear microscopy, performed in just one day;

• bacteriological examination (culture) - the "gold standard" in the diagnosis of tuberculosis - takes 3 to 8 weeks. Using the automated system VASTES MGIT960 reduces the study, compared with classical sowing to 5-42 days. The more mycobacteria in sputum samples, the faster you can get the answer;

• molecular genetic studies on tuberculosis drug susceptibility testing of Mycobacterium tuberculosis.

Rapid method for diagnosis of tuberculosis by polymerase chain reaction (PCR) in real time Xpert MTB / RIF can detect Mycobacterium tuberculosis in a sample of sputum and rifampicin resistance for 2 hours. Rapid molecular genetic method (Hein-test) can detect Mycobacterium tuberculosis and to determine the sensitivity to other anti-TB drugs for 2 days. These methods vyyavlyut Mycobacterium tuberculosis DNA fragments. Based on the results of this study we can confidently diagnose and choose the individual treatment specifically "a man."

2. Radiation diagnostics. All patients suspected of having pulmonary tuberculosis, to eliminate the disease held digital radiography. If you need to perform computed tomography.

Videothoracoscopy - a method of surgery using endoscopic equipment. It enables the diagnosis and differential diagnosis of nonspecific pulmonary diseases and tuberculosis, to confirm the diagnosis by histological analysis, obtained by VATS biopsy (tissue slices of the affected organ).

Treatment of tuberculosis. Treatment of tuberculosis in Belarus is carried out in line with international standards. Belarus first in Europe to use of new anti-TB drugs (bedakvilina, delamanida, clofazimine, linezolid, imipenem).

Use a method of treatment with autologous (own) multipotent mesenchymal stromal cells.

Controlled intake of drugs with individual selection for each patient and treatment with all available anti-TB drugs in accordance with international standards allows to achieve success in the treatment of the patient.

Modern methods in the hands of experienced physicians can properly establish the diagnosis in a timely manner to appoint adequate treatment of TB with individual selection of medicines and cure the patient of tuberculosis and nonspecific pulmonary diseases. Thanks to the introduction of modern technologies in the leading medical institutions of the country achieved high efficiency of treatment - bacteriological achieved in 100% of patients.